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Jeanne McAdara-Berkowitz, Ph.D.

Principal

Jeanne possesses a unique mix of experience that includes 9 years as a biomedical research scientist and another 10 years in integrated marketing for the health science industry.

As principal of Biolexica, Jeanne consults for biotechnology and healthcare companies, and agencies serving those industries. She has been responsible for a wide range of scientific communication projects, from the drafting of peer-reviewed scientific papers, bylined articles for medical trade journals and white papers to integrated marketing projects such as corporate messaging and branding, Web site and collateral development. Her work has covered a broad range of scientific and clinical disciplines, including oncology (solid and hematologic tumors), cardiology, neurology, immunology, rheumatology, metabolic disorders, urology, audiology, surgical technologies, and applied drug discovery and development.

Before founding Biolexica, Jeanne worked for FischerHealth, a strategic communication firm dedicated solely to the healthcare industry and a member of the Porter Novelli family of companies. Prior to that, Jeanne was a postdoctoral research fellow at the UCLA Jonsson Comprehensive Cancer Center where she studied the role of the HOX family of homeobox genes and the c-Fes tyrosine kinase in myeloid differentiation and leukemogenesis. While at UCLA she was awarded a postdoctoral research fellowship from the National Institute of Dental Research to study head and neck cancers.

Before working at UCLA, Jeanne was a doctoral candidate at The Scripps Research Institute. Her dissertation research, funded by an American Heart Association pre-doctoral fellowship, resulted in the discovery of a novel protein subunit of the neutrophil NADPH oxidase.

Jeanne is a member of the American Medical Writers Association and the Colorado BioSciences Association. She received her Bachelor of Arts degree in Biology from the College of Creative Studies at the University of California at Santa Barbara, and her Ph.D. in Macromolecular and Cellular Structure and Chemistry from the Scripps Research Institute in La Jolla, California. She lives in Colorado.

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Publications

Refereed scholarly journal articles (client):

• Fallon A, Goodchild T, Wang R, Matheny RG. Remodeling of extracellular matrix patch used for carotid artery repair. J Surg Res. In Press
• Ruidiaz ME, Cortes-Mateos MJ, Sandoval S et al. Quantitative comparison of surgical margin histology following excision with traditional electrosurgery and a low-thermal-injury dissection device. J Surg Oncol. 2011;104:746-754.
• Cho H, Daniel T, Buechler YJ et al. Optimized clinical performance of growth hormone with an expanded genetic code. Proc Natl Acad Sci U S A. 2011;108:9060-9065.
• Fine RE, Vose JG. Traditional electrosurgery and a low thermal injury dissection device yield different outcomes following bilateral skin-sparing mastectomy: a case report. J Med Case Reports. 2011;5:212.
• Ruidiaz ME, Messmer D, Atmodjo DY et al. Comparative healing of human cutaneous surgical incisions created by the PEAK PlasmaBlade, conventional electrosurgery, and a standard scalpel. Plast Reconstr Surg. 2011;128:104-111.
• Chang EI, Carlson GA, Vose JG, Huang EJ, Yang GP. Comparative healing of rat fascia following incision with three surgical instruments. J Surg Res. 2011;167:e47-54.
• Boyd WD, Johnson WEr, Sultan PK, Deering TF, Matheny RG. Pericardial reconstruction using an extracellular matrix implant correlates with reduced risk of postoperative atrial fibrillation in coronary artery bypass surgery patients. Heart Surg Forum. 2010;13:E311-6.
• Zhao ZQ, Puskas JD, Xu D et al. Improvement in cardiac function with small intestine extracellular matrix is associated with recruitment of C-kit cells, myofibroblasts, and macrophages after myocardial infarction. J Am Coll Cardiol. 2010;55:1250-1261.
• Gerdisch MW, Akinwande AO, Matheny RG. Use of a novel acellular xenograft as a patch for aortic annular enlargement during aortic valve replacement. Innovations. 2010;5:60-62.
• Loh SA, Carlson GA, Chang EI, Huang E, Palanker D, Gurtner GC. Comparative healing of surgical incisions created by the PEAK PlasmaBlade, conventional electrosurgery, and a scalpel. Plast Reconstr Surg. 2009;124:1849-1859.
• Vose JG, McAdara-Berkowitz J. Reducing scalpel injuries in the operating room. AORN J. 2009;90:867-872.

Refereed scholarly journal articles (personal):

• Carlson A, Berkowitz JM, Browning D, Slamon DJ, Gasson JC, Yates KE. Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias. DNA Cell Biol. 2005;24:311-316.
• McAdara Berkowitz JK, Catz SD, Johnson JL, Ruedi JM, Thon V, Babior BM. JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. J Biol Chem. 2001;276:18855-18862.
• Yaron Y, McAdara JK, Lynch M, Hughes E, Gasson JC. Identification of novel functional regions important for the activity of HOX B7 in mammalian cells. J Immunol. 2001;166:5058-5067.
• Fuller JF, McAdara J, Yaron Y, Sakaguchi M, Fraser JK, Gasson JC. Characterization of HOX gene expression during myelopoiesis: role of HOX A5 in lineage commitment and maturation. Blood. 1999;93:3391-3400.
• Inanami O, Johnson JL, McAdara JK et al. Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47^PHOX on serine 303 or 304. J Biol Chem. 1998;273:9539-9543.

Doctoral dissertation:

• McAdara, JK. Cloning and Characterization of p62^MCSP: A Novel Membrane Trafficking Protein Associated with the Leukocyte NADPH Oxidase, Apr 1998.

General interest articles:

• McAdara-Berkowitz, J. Jump, Don't Fall into Your Career Transition. ASBMB Today. December 2009.
• McAdara-Berkowitz, J. Blending Ergonomics and Microscopy. The Scientist. 17(12): 36, Jun. 16, 2003.
• McAdara, J. Wired. The Scientist. 14(13): 20, Jun 26, 2000.
• McAdara, J. Inner Sanctum. The Scientist. 14(11): 25, May 29, 2000.
• McAdara, J. Check it Out. The Scientist. 14(10): 18, May 15, 2000.  
• McAdara, J. A Step Ahead. The Scientist. 14(7): 24, Apr 3, 2000.
• McAdara, J. The Resolution Solution. The Scientist. 14(3): 24, Feb 7, 2000.
• McAdara, J. Have Lab, Will Travel. The Scientist. 13(22): 16, Nov 8, 1999.